CLINICAL SIGNIFICANCE OF MICROALBUMINURIA IN FORMATION OF VASCULAR DISEASES OF POSTERIOR EYE SEGMENT IN WOMEN After PREECLAMPSIA, POSSIBILITIES OF PROGNOSIS
Oleg Vladimirovich KOLENKO1,2, Natalya Viktorovna POMYTKINA1, Evgeniy Leonidovich SOROKIN1, Galina Vsevolodovna CHIZHOVA2, Yaroslav Evgen’evich PASHENTSEV1, Yuriy Nikolaevich BERDAKOV3
1S. Fyodorov Eye Microsurgery Federal State Institution of Minzdrav of Russia, Khabarovsk Branch
2Postgraduate Institute for Public Health Workers of Minzdrav of Khabarovsk Region
3Perinatal center of Minzdrav of Khabarovsk region
Keywords: преэклампсия, микроальбуминурия, сосудистая патология заднего отрезка глаза, preeclampsia, microalbuminuria, vascular pathology of posterior eye segment
Abstract
The purpose of study is to assess the clinical significance of microalbuminuria (MAU) in pregnant women with preeclampsia in formation of vascular eye pathology in long-term postpartum period. Material and methods. In retrospect, according to medical records, analysis of somatic condition of 114 women who had preeclampsia during pregnancy was carried out, and presence / absence of MAU during pregnancy were determined. MAU was detected in the 3rd trimester of pregnancy using test strips «Woerhringer Ingelheim» (Austria), considering the test to be positive with a value of 30 mg/day and more. The age of women at time of research was from 24 to 52 years, the period after suffering preeclampsia was 12.5 ± 6.5 years. Two groups were formed: the main - 35 women with initial MAU during pregnancy; the comparison - 79 women who had no MAU during pregnancy. The controls were 36 women with physiological pregnancy and delivery. Results and discussion. In period after delivery, vascular diseases of posterior eye segment occurred in 14 people in the main group (40 %) and 15 people in the comparison group (19 %). In the control group in this period, vascular pathology of posterior eye segment was formed in 2 women. Conclusion. Statistically significant increase of frequency of formation of vascular pathology of posterior eye segment in postpartum period was revealed in women, who had pregnancy complicated by preeclampsia and MAU in the 3rd trimester, which increased through 10 and more years after delivery. The initial presence of MAU during pregnancy can be the marker of increased risk of formation of vascular pathology of posterior eye segment at different periods of the postpartum period.
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