CORRELATION BETWEEN OBESITY AND TESTOSTERONE LEVEL, ANXIETY SYMPTOMS, DEPRESSION AND ACCELERATED AGING IN MEN
Olga Vasil'evna VASILEVA, Vera Georgievna SELYATITSKAYA
Research Institute of Experimental and Clinical Medicine
Keywords: мужчины, тестостерон, андрогенный дефицит, тревога, депрессия, эректильная дисфункция, ожирение, ускоренное старение, men, alarm, depression, androgen deficiency, erectile dysfunction, obesity, accelerated aging
Abstract
The aim of the investigation was to study the relationship of blood testosterone levels with the severity of anxiety signs, depression and urological pathology symptoms in men of mature age with normal weight, overweight and obesity. Material and methods: 188 men of 36.7 average age participated in the study. Anthropometric examination was carried out, the HADS questionnaire (Hospital Anxiety and Depression Scale, 1983) was used to assess the level of anxiety and depression; the severity of urinary disorders symptoms was evaluated with the scale of IPSS (International Prostate Symptom Score). To study the sexual dysfunction the international index of erectile dysfunction (ICEF-5) was applied. AMS Men's Age Symptoms (Aging Males Symptoms) questionnaire was used to identify clinical signs of androgen deficiency. The content of testosterone and cortisol in blood serum was determined by EIA. Results and discussion: The growth of androgen deficiency along with the increase in the urinary disorders symptoms, extended anxiety, depression and enhanced signs of erectile dysfunction have been revealed in men with overweight and obesity relating to the men with normal body weight. The androgen deficiency growth influences the aging processes acceleration. In turn, the presence of urological pathology in men can plays an important role in the obesity pathogenesis through the increase in anxiety and depression.
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