STRUCTURAL CHARACTERIZATION, PHOTOPHYSICAL AND BSA BINDING INTERACTION STUDIES OF 4,4'-bis(BENZIMIDAZOLYL)-2,2'-BIPYRIDINE
K. Swarnalatha1, P. Rathnamala1, A.A. Babu1, N. Bhuvanesh2
1Manonmaniam Sundaranar University, Tirunelveli, Tamil Nadu, India
2University of Texas at Austin, Austin, USA
Keywords: 4,4'-bis(benzimidazolyl)-2,2'-bipyridine, crystal structure, energy transfer, BSA binding
Abstract
The title compound is synthesized from the precursors 1,2-diaminobenzene and 2,2¢-bipyridine-4,4¢-dicarboxylic acid (dcbpy) and characterized using ESI-Mass, 1H NMR, FT-IR and single crystal X-ray analysis. We are the first to report the crystal structure of the 4,4¢-bis(benzimidazolyl)-2,2¢-bipyridine (bimbpy) ligand. The photophysical properties of the compound in dimethyl sulfoxide and in the aqueous medium are studied. The interaction studies of bimbpy with bovine serum albumin (BSA) were performed with the fluorescence technique and it strongly binds with BSA.
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