HYPOLIPIDEMIC MEDICATIONS: CURRENT USE AND FUTURE PERSPECTIVES. PART 1. NON-STATIN HYPOLIPIDEMIC MEDICATIONS
A. E. Bagriy, A. I. Dyadyk, M. V. Khomenko, I. N. Tsiba, V. A. Efremenko, E. V. Shchukina, O. A. Prikolota
Donetsk national medical university named after M.Gorkiy, Ukraine, Donetsk, 83003, av. Illicha, 16
Keywords: не-статиновые гиполипидемические средства, фибраты, препараты никотиновой кислоты, эзетимиб, секвестранты желчных кислот, полиненасыщенные жирные кислоты, ингибиторы фермента PCSK9, non-statin hypolipidemic drugs, fibrates, nicotinic acid, resins, polyunsaturated fatty acids, ezetimibe, PCSK9-inhibitors
Abstract
This article is devoted to discussion about main aspects of current use of non-statin hypolipidemic drugs according last international guidelines (including fibrates, nicotinic acid, resins, polyunsaturated fatty acids, ezetimibe, PCSK9-inhibitors). For each group mechanism of action, effects on lipid profile, main results of randomized trials and practical use approaches are shortly represented.
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