Responses of Hepatic Biochemical Markers of the Bream Abramis brama L. on Polychlorinated Biphenyls Administered with Food
A. A. MOROZOV, V. V. YURCHENKO
I. D. Papanin Institute for Biology of Inland Waters, RAS, 152742, Yaroslavl Oblast, Borok
Keywords: лещ, антиоксидантная система, перекисное окисление липидов, система биотрансформации ксенобиотиков, полихлорированные бифенилы, эксперимент, bream, antioxidant system, lipid peroxidation, biotransformation system, polychlorinated biрhenyls, experiment
Abstract
The article presents the results of an experimental study on the bream Abramis brama L. exposed to polychlorinated biрhenyls (PCBs) administered with food. Responses of the components of hepatic biotransformation system (activity of ethoxyresorufin-O-deethylase and glutathione-S-transferase), antioxidant system (superoxide dismutase and catalase activity) and lipid peroxidation system (conjugated dienes and malonic dialdehyde contents) were studied. It was determined that the 2 mg/kg dose of PCBs did not cause permanent physiological alterations in the bream exposed to such feed for 14 days. Apparently, at these exposure conditions hepatic protection systems of the bream were able to suppress effects of xenobiotics and keep destructive processes on a stable moderate level.
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