DYSLIPIDEMIA – IMPORTANT PROGNOSTIC UNFAVORABLE COURSE RISK FACTOR OF MULTIFOCAL ATHEROSCLEROSIS IN MAN AFTER CAROTID ENDARTERECTOMY
A.V. Frolov1,2, O.L. Barbarash1,2
1Research Institute for Complex Studying of Cardiovascular Diseases, Russian Academy of Medical Sciences, 6 Sosnovy blvd, Kemerovo, 650002, Sosnovy, Russian Federation
2Department of Cardiology and Cardiovascular Surgery, State Kemerovo Medical Academy, 22a Voroshilov str., 650029, Russian Federation
Keywords: prognosis, risk factors, dyslipidemia, atherosclerosis, carotid endarterectomy
Abstract
156 man, who were in the surgical department for subsequent reconstructive operation of carotid arteries, were analyzed. Depending on long-term one-year prognosis all patients have been divided into two groups: with unfavorable (93 individuals – 59.6 %) and favorable (63 individuals – 40.4 %) prognosis. It is proved that cardiovascular complications risk such as stroke, transient ischemic attack, myocardial infarction, patients death, and courses deterioration of multifocal atherosclerosis in any arterial region, increase or clinical presentations onset of ischemia in any organ during the first year after surgical procedure increases if there is dyslipidemia in preoperative period, pathologic value of ankle-brachial index (less than 0.9), besides intraoperative characteristic of atherosclerotic plaque (occurrence of intraplaque haemorrhage and extent of atherosclerotic plaque more than 2 cm) in patients. But among this prognostic factors the most important one is the dyslipidemia, herewith statistic regression coefficient of which is 4.64 and Wald index is 43.1. All these data determine maximal prognostic value of dyslipidemia versus other risk factors.
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