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Chemistry for Sustainable Development

2013 year, number 6

Nanosized Magnetic Powder on the Ground of Oxides in Medicine and Biology

O. G. TEREKHOVA1, A. A. MAGAEVA1 and E. P. NAIDEN1,2
1Department of Structural Macrokinetics, Tomsk Scientific Centre, Siberia Branch of the Russian Academy of Sciences, Pr. Akademicheskiy 10/4, Tomsk 634021 (Russia)
E-mail: terog@dsm.tsc.ru
2Tomsk State University, Pr. Lenina 36, Tomsk 634050 (Russia)
Keywords: oxide nanoferrimagnetics, mechanochemical synthesis, adsorption onto nanoparticles, magnetofection
Pages: 621–628

Abstract

A method is presented for producing nanosized oxide ferromagnetics from salt systems with the use of the mechanochemical activation and their fundamental properties are investigated. Results concerning the use of the oxide ferrimagnetics synthesized for the magnetofection of DNA, DNA/RNA sorption, microbial cells, proteins, and contrast agents for MRT diagnostics are reported. It has been found that nanoparticles are non-toxic; their distribution in internal organs and the decrease dynamics, the possibility of using them for medication transport have been demonstrated.