State of hypolipidemic therapy and its efficiency for patients with coronary heart disease after acute coronary events (over the Russian cooperative investigation "Physical training at the post-hospital stage of rehabilitation after acute coronary incidents")
D.M. Aronov, V.B. Krasnitsky, M.G. Bubnova
State Research Center for Preventive Medicine
Keywords: coronary heart disease, dislipidemia, physical training, hypolipidemic therapy under the conditions of polyclinic
Pages: 12-19
Abstract
Application and efficiency of hypolipidemic therapy in comparison with the effect of physical training on the dynamics of blood lipids in patients suffering from coronary heart disease after acute coronary events was studied. We examined 392 patients from 11 scientific medical centers and 9 establishments of public health care in Russia. The patients were randomized into the intervention group (197 persons) and the reference group (195 persons). Confirmations of the positive effect of physical training on the level of cholesterol of HDL and atherogeneity coefficients were obtained. In the basic group, a decrease in the level of total cholesterol and increase in cholesterol of HDL turned out to be statistically significant. Differences in the dynamics of total cholesterol, cholesterol of HDL and the ratio of the former to the latter for the comparison between the groups were reliable in favor of the basic group. High efficiency of physical training in the elevation of HDL and decrease in atherogeneity index was stated.
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