Mechanisms of Short-Term Thermal Compensatory-Adaptive Reaction of the Fish Liver of Carassius auratus gibelio Species
E. I. Antonova
Keywords: liver, hepatocytes, hyperthermia, compensatory-adaptive reaction, fish, oxidoreductase, caspase-3, programmed cell death
Pages: 79-85
Abstract
After an hour of the action of hyperthermia on an organism of the Carassius aurata gibelio Bloch fish species, a number of metabolic reactions in liver get blocked and simultaneously the cascade of reciprocal processes acquired during evolution. With the development of metabolic depression, the activity of the enzymes of citric acid cycle - mitochondrial NADIDG increases by 20.4 %, while the activity of mitochondrial NADMDG decreases by 10.2 %; glycolysis process gets activated by 50.2 %, the activity of caspase-3 and acid phosphatase increases depicting the development of the programmed ways of hepatocyte destruction on the way to apoptosis, autophagia and necrosis. The early regeneration processes are initiated.
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