Studying the Dynamics of Changing the Concentration of Acetate Ions in the Blood of Patients in the Course Dialysis Method Using Capillary Electrophoresis
Z. M. UNAROKOV1, O. V. SHUVAEVA2 and T. V. MUKHOEDOVA1
1 Meshalkin Novosibirsk Research Institute of Circulation Patology, Ul. Rechkunovskaya 15, Novosibirsk 630055 (Russia),
E-mail: jovi33@rambler.ru
2 Nikolaev Institute of Inorganic Chemistry, Siberian Branch of the Russian Academy of Sciences, Pr. Akademika Lavrentyeva 3, Novosibirsk 630090 (Russia)
Keywords: capillary electrophoresis, acetate ion, acetate-free dialysis, SLED
Pages: 555–560
Abstract
The content of acetate ions in the blood of patients after cardiac surgery in the course of hemodialysis using different dialyzing solutions was investigated for the first time. Using the method of capillary electrophoresis it was revealed that in the case when the bicarbonate dialysate contains acetate ions in a small amount (3 mmol/L), the concentration thereof in blood exhibits a 12-fold increase, which causes enhancing the risk of cardiovascular instability in the course of hemodialysis.
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