Development of the Method of Obtaining Betulin Diacetate and Dipropionate from Birch Bark
S. A. Kuznetsova, B. N. Kuznetsov, G. P. Skvortsova, N. Y. Vasilyeva, E. S. Skurydina, G. S. Kalacheva
Keywords: birch bark, acylation, betulin diacetate, dipropionate, identification
Pages: 313-320
Abstract
Methods of synthesis of betulin diacetate and dipropionate from birch bark are proposed. The methods are based on combined extraction of betulin from birch bark and its acylation with acetic and propionic acids. The structure of the resulting betulin derivatives was confirmed by means of chromatography - mass spectrometry, FTIR and NMR spectroscopy.
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