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Chemistry for Sustainable Development

2004 year, number 2

Natural Halogenated Polyethers, Pyrones, Coumarins and Flavones

VALERY M. DEMBITSKY1 and GENRICH A. TOLSTIKOV2
1Department of Pharmaceutical Chemistry and Natural Products,
School of Pharmacy, The Hebrew University of Jerusalem,
P.O. Box 12065, Jerusalem 91120 (Israel), E-mail: dvalery@cc.huji.ac.il
2Vorozhtsov Novosibirsk Institute of Organic Chemistry,
Siberian Branch of the Russian Academy of Sciences,
Pr. Akademika Lavrentyeva 9, Novosibirsk 630090 (Russia), E-mail: gtolstik@nioch.nsc.ru
Pages: 129-138

Abstract

Halogenated polyethers, pyrones, coumarins and flavones compose four comparatively small but interesting groups of natural compounds. Some of these compounds are antibiotics, toxins or biologically active substances. They have been found in microorganisms, e. g. cyanobacteria, fungi, plants, algae and in invertebrates. Structures of about 100 compounds have been considered, and data on their biological activity presented.